Candida Blood Stream Infections in Neonates
نویسنده
چکیده
Candida spp. are known to be the most common fungal pathogens isolated from blood cultures of neonates. The present study was undertaken to know the prevalence of candidemia in neonates and their antifungal susceptibility pattern. Candida isolates were speciated by using germ tube, carbohydrate assimilation and fermentation tests, CHROM agar and Dalmau plate culture method. Antifungal susceptibility testing to amphotericin B and fluconazole was done using E-test. A total of 56 Candida isolates were obtained over a period of one year from neonates. Of these 42 isolates were non-albicans Candida. All the isolates were sensitive to amphotericin B. Fluconazole was more commonly observed in non-albicans Candida. Candida speciation as well as antifungal susceptibility pattern need to be studied,especially in light of increasing drug resistance and newer antifungals to be evaluated for therapy.
منابع مشابه
Candida Blood Stream Infection in Neonates: Experience from A Tertiary Care Teaching Hospital of Central India.
OBJECTIVE To assess the epidemiology of neonatal Candida blood stream infection. METHODS Medical records of neonates with Candida blood stream infection over 5 years (September 2010 to August 2015) were reviewed. Clinical details, species distribution and antifungal susceptibility were noted. RESULTS 114 neonates developed Candida blood stream infection. Commonly isolated Candida species we...
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